Endocrine Abstracts

Aims: The majority of patients with Cushing's disease have pituitary microadenomas and preoperative localization can be helpful during transphenoidal surgery. Inferior petrosal sinus sampling (IPSS) of ACTH and responses to CRH may show higher levels on the side ipsilateral to the tumour, although this remains controversial. A few small studies suggested a prolactin response to CRH during IPSS. We assessed whether prolactin responses to CRH can help lateralize the microadenoma...